Charles Fazzino is most well-known for the three-dimensionality of his limited edition silkscreen serigraphs.

In 1980, while exhibiting in the juried arts fairs in Florida, Charles Fazzino attended a 3-D paper tole class in an arts supply store. He experimented with the technique and showed his first three-dimensional print at the Greenwich Village Art Show in New York City in May, 1980.

Fazzino entered the gallery circuit when he sold his first 3-D offset lithographs to a gallery in Michigan.